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Basic Immunology Concepts

 

Innate Immune System Overview
Created by Juanita Valdes Camacho, MD

Adaptive Immune System Overview
Created by Aisha Ahmed, MD

 

 
Cells of the Immune System

 

Neutrophil
Created by Samira Jeimy, MD PhD

Macrophage
Created by Erin L. Reigh, MD

Mast Cell
Created by Drew A. White, MD FAAAAI

Eosinophil
Created by Drew A. White, MD FAAAAI

B Cell 
Created by Anna Kovalszki, MD FAAAAI

T Helper Cell Subtypes (Th1)
Created by Margaret Redmond, MD FAAAAI

T Helper Cell Subtypes (Th2)
Created by Stokes Peebles Jr., MD FAAAAI

T Helper Cell Subtypes (Th17)
Created by Heather K. Lehman, MD FAAAAI

CD8 T Cell
Created by Margaret Redmond, MD FAAAAI

NK Cell
Created by Samira Jeimy, MD PhD

ILC2 Cells
Created by Stokes Peebles Jr., MD FAAAAI

 

 

 

 
Secondary Immune Organs

 

Lymphoid Tissue Structure and Function 
Created by Sean A. McGhee, MD FAAAAI

Cell Movement (Selectins, Integrins)
Created by Christopher Chang, MD PhD FAAAAI

 

 

Innate Immune Function

 

Type I interferons
Created by Christopher Chang, MD PhD FAAAAI

Innate inflammation (Inflammasome)
Created by Christopher Chang, MD PhD FAAAAI

Complement Cascade
Created by Amika Sood, MD

Complement Regulation
Created by Heather K. Lehman, MD FAAAAI

 

 

Adaptive Immune Function

 

B Cell Development
Created by Erin L. Reigh, MD

T Cell Development (APECED)
Created by Rebecca R. Saff, MD PhD FAAAAI

B cell and T Cell Receptor Generation (RAG deficiency)
Created by Amika Sood, MD

MHC Class I Processing 
Created by Rebecca R. Saff, MD PhD FAAAAI

MHC Class II Processing 
Created by Rebecca R. Saff, MD PhD FAAAAI

T Cell Signaling 
Created by Juanita Valdes Camacho, MD

NFkB Signaling (NEMO)
Created by Anna Kovalszki, MD FAAAAI

B Cell Signaling
Created by Rebecca R. Saff, MD PhD FAAAAI

Antibody Function
Created by Anna Kovalszki, MD FAAAAI

Class Switching (CD40L Deficiency)
Created by Margaret Huntwork, MD

Somatic Hypermutation 
Created by Margaret Huntwork, MD

 

 

 

Immunology Lab Tests

 

Flow Cytometry (How to do it, FSC vs SSC, markers)
Created by Rebecca R. Saff, MD PhD FAAAAI

DHR Testing
Created by Craig D. Platt, MD PhD