2015 VAM: 4302 - Innate Immunity in Food Allergy: Lessons Learned From Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is an inflammatory disease characterized by a cellular infiltrate which includes eosinophils, invariant natural killer cells (iNKTs), basophils, mast cells and T-cells that produce Th2 cytokines (i.e. IL-4 and IL-13). Similar to other atopic diseases, EoE is triggered by environmental and food allergens. This symposium explores the evidence that links epithelial cells, basophils, and iNKT cells to EoE.
AMA PRA Category 1 Credits™: 1.25
Credit must be claimed by June 30, 2017. Any credit request on or after July 1, 2017 will be subject to an administrative fee.
Allied Health Professionals
Upon completion of this activity participants will be able to:
1. Discuss the role of esophageal epithelial cells in modifying immunologic responses in EoE
2. Discuss the importance of basophils in the pathogenesis of EoE
3. Discuss the current understanding of invariant NK cells in disease manifestations and immune responses in EoE
Dr. Marc E. Rothenberg, MD PhD FAAAAI, Children's Hospital Medical Center, Cincinnati, OH
Dr. Mark C. Siracusa, PhD, Rutgers New Jersey Medical School, Newark, NJ
Dr. Antonella Cianferoni, MD PhD FAAAAI, The Children's Hospital of Philadelphia, Philadelphia, PA
- 1.25 AttendanceAttendance credit.
- 1.25 CECE credit.
- 1.25 CMECME credit.