VAM 20 1212: New Developments in Mechanisms of Aspirin-Exacerbated Respiratory Disease (AERD)

Session 1212 includes the following talks:

  • Insights into Mast Cell Dysregulation in AERD: Transcriptional Profiling of Sinus Tissue Mast Cells
  • Innate Lymphoid Cell Recruitment and Activation in AERD
  • Regulation of Local Immunoglobulin Production in Nasal Tissues: A Key to Pathogenesis
  • Epithelial Barrier Dysregulation in Nasal Polyp and Asthma Pathogenesis
  • ILC2s in Nasal Polyps
  • Molecular Phenotyping of Asthma Using Profiles of Urinary Lipid Mediators
  • Control of Mast Cell Function in AERD

The American Board of Allergy and Immunology (ABAI) has approved this activity for 3.00 MOC Part ll Self-Assessment credits.  These credits will be awarded once you have completed all components of the course.  

Target Audience

  • Physicians
  • Allergists/Immunologists
  • Nurses
  • Nurse Practitioners
  • Allied Health Professionals

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Recognize the importance of local immunoglobulin production in the pathogenesis and severity of nasal polyposis.
  • Describe the diversity of transcriptionally distinct mast cell subsets in nasal polyps and their likely contributions to disease pathogenesis.
  • Recognize the role of lipid mediators and their receptors in asthma and AERD pathogenesis
Available credit: 
  • 3.00 Attendance
    Attendance credit.
  • 3.00 CE
    CE credit.
  • 3.00 CME
    CME credit.
Course opens: 
Course expires: 
Planning Committee

See attachment at bottom of page for Annual Meeting Program Committee disclosure information.


Katherine Cahill, MD
Vanderbilt University Medical Center,  Nashville, TN
Relevant relationships: Novartis (Advisory Board)

Noam Cohen, MD PhD
University of Pennsylvania, Philadelphia, PA
Relevant relationships: None

Taylor Doherty, MD FAAAAI
UC San Diego, San Diego, CA
Relevant relationships: None

Daniel Dwyer, PhD
Harvard Medical School, Boston, MA
Relevant relationships: None

Kathryn Hulse, PhD
Northwestern University, Evanston, IL
Relevant relationships: None

Atsushi Kato, PhD
Northwestern University, Feinberg School, Chiacgo, IL
Relevant relationships: Astellas Pharma (Consultant)

Atsushi Kolmert, PhD
Karolinska Institutet, Stockholm, Sweden
Relevant relationships: None

COI Reviewers

Robert Corriel, MD FAAAAI
Manhasset Allergy and Asthma Associates, Manhasset, NY
Relevant relationships: None

Maria Crain, RN MA CPNP
Children's Medical Center, Dallas, TX
Relevant relationships: Aimmune: food allergy oral immunotherapy

Bruce J. Lanser, MD FAAAAI
National Jewish Health, Denver, CO
Relevant relationships: Aimmune: peanut oral immunotherapy

AAAAI Disclosure Policy

Pursuant to the Code of Ethics for the American Academy of Allergy, Asthma & Immunology (AAAAI) and the Standards for Commercial Support of Continuing Medical Education of the Accreditation Council for Continuing Medical Education, the AAAAI requires disclosure of certain information from faculty members of educational activities designated for CME credit by the AAAAI. Prior to the activity, authors and reviewers are required to disclose all relationships that meet the following parameters:

  • Employment. Name of employer and job title.
  • Financial interests. All organizations, other than the employer, from which the faculty member or a member of his/her immediate family or household receives annual remuneration in any amount (including grants, honoraria and consulting fees).
  • Research interests. All organizations which support research projects for which the faculty member or member of his/her immediate family or household serves as an investigator.
  • Legal Consultation Services/Expert Witness Testimony: All topics on which the faculty member provided legal consultation and/or expert witness testimony during the previous calendar year.
  • Organizational interests: All organizations, other than the AAAAI, for which the faculty member holds volunteer positions.
  • Gifts. All organizations from which the faculty member or a member of his/her immediate family or household have received a gift of any amount in the last year.
  • Other interests. All interests of the faculty member or a member of his/her immediate family or household that would be judged by a majority of his/her peers to be more than casual and/or likely to impact his/her ability to exercise independent judgment. This includes any financial interest in or relationship with any manufacturer of a commercial product, and any financial interest or relationship with any organization that provides commercial support to AAAAI-sponsored educational activities.

The information disclosed by the speakers and planning committee was reviewed in accordance with the AAAAI Disclosure Policy. All potential conflicts of interest were resolved by the planners, faculty, and reviewers prior to their participation in the development of this activity.

Accreditation Statement

The American Academy of Allergy, Asthma and Immunology (AAAAI) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation Statement

The American Academy of Allergy, Asthma & Immunology designates this enduring material for a maximum of 3.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CE Designation Statement

The American Academy of Allergy, Asthma, & Immunology (AAAAI) is a Provider, approved by the California Board of Registered Nursing, Provider #10704, for up to 3.00 Contact Hours.

Credit Claiming Period

Credit claiming for this activity will expire at 11:59 pm on May 31, 2022. Requests to claim credit on or after June 1, 2022 will be subject to an administrative fee.

AAAAI Privacy Policy

To verify your participation in educational activities, you may be asked to provide your name, contact information, and/or other descriptors. The AAAAI will not release this information to outside entities. It may be used internally to inform you of other AAAAI educational activities. If you wish to have your information excluded from this process, please contact us at


Activity related questions should be directed to

Available Credit

  • 3.00 Attendance
    Attendance credit.
  • 3.00 CE
    CE credit.
  • 3.00 CME
    CME credit.


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