2016 VAM: 1202 - Diagnostic Challenges in Mastocytosis: Serum Tryptase, Allele-Specific PCR and GI Pathology
The problem of evaluating an elevated serum tryptase value is common and widespread. The significance of the elevation depends on several factors that can be sorted out using a comprehensive understanding of the probabilities of mastocytosis, familial tryptasemia and mast cell activation disorder and currently available laboratory tests.
In this session, several paradigms for predicting mastocytosis on the basis of clinical findings and laboratory tests will be discussed. The appropriate subsequent tests and the indications/non-indications for bone marrow biopsy will also be reviewed.
AMA PRA Category 1 Credits™: 2.50
Credit must be claimed by May 31, 2018. Any credit request on or after June 1, 2018 will be subject to an administrative fee.
Allied Health Professionals
Upon completion of this session, participants should be able to:
1. Discuss utility and interpretation of elevated tryptase level
2. Discuss which cases can be evaluated at general allergist level and when a referral to a mastocytosis center is indicated
3. Discuss utility and interpretation of allele-specific PCR and indications for bone marrow biopsy
Dr. Joseph H. Butterfield, MD FAAAAI, Mayo Clinic, Rochester, MN
Patrizia Bonadonna, MD CME, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
Joseph H. Butterfield, MD FAAAAI, Mayo Clinic, Rochester, MN
Dean D. Metcalfe, MD FAAAAI, NIAID, NIH, Bethesda, MD
Alberto Orfao, MD PhD, Spanish Network on Mastocytosis (REMA), Salamanca, Spain
- 2.50 AttendanceAttendance credit.
- 2.50 CECE credit.
- 2.50 CMECME credit.