
AAAAI-NAIA/JACI: In Practice Virtual Journal Club: June 4, 2025
| Registration Type | Registration Price |
|---|---|
| AAAAI Member | Free |
| Non-Member | $25 |
If you are a AAAAI Member and would like to register your staff for this event please email [email protected] for a coupon code
Asthma and food allergy are common conditions managed by allergist/immunologists, and new therapy is welcome for both conditions. Regarding asthma, the relatively recent introduction of biologics has revolutionized the care of patients with severe asthma, but not all patients with severe asthma improve with biologic therapy. The first study explored the relationship between mucus plugging on chest CT scans and responsiveness to biologic therapy. The study showed that higher degrees of mucus plugging correlates with worse pulmonary function at baseline but also predicts a larger clinical and pulmonary function response to biologic therapies in severe asthma. These results suggest that the degree of mucus plugging can be useful in the selection of candidates for biologic therapy among patients with severe asthma.
Regarding food allergy, peanut allergy is a particularly common and negatively impactful example. Although the classic treatment has been avoidance, the ubiquity of peanut in the diet makes avoidance difficult, and accidental peanut exposure is common and often results in severe reactions. More recently, oral desensitization and omalizumab have been approved for the treatment of peanut allergy, but both treatments come with drawbacks in young children. The second article describes the long-term follow-up of an another form of desensitization, epicutaneous immunotherapy. The study found that after 24 months of epicutaneous peanut patch immunotherapy started in children 1-3 years of age, there was continued enhancement of the treatment effect without additional reports of treatment-related systemic allergic reactions, demonstrating the potential of epicutaneous immunotherapy to be a safe and efficacious treatment option for the management of young peanut-allergic children
The thorough discussion of the strengths, limitations, and clinical applicability of these articles by experts in the field that is provided in the Virtual Journal Club format should allow the listener to use the information in these studies most appropriately in their clinical practice.
The June 4, 2025 webinar will focus on two journal articles:
Moderator: Christine Panganiban, MD MS
NAIA Speaker: Ross Tanis, MD
Mentor Speaker: Gerald Teague, MD
Speaker: Brynne Underwood, MD
Mentor Speaker: Michelle Huffaker, MD FAAAAI
Target Audience
- Allergist/Immunologists
- Fellows-in-Training
Learning Objectives
Upon completion of this activity, participants should be able to:
- Recognize the relationship of mucus plugging to baseline severity and response to biologic treatment in patients with severe asthma
- Discuss the two-year safety and efficacy data regarding peanut epicutaenous immunotherapy in the treatment of young children with peanut allergy
The information disclosed by the speakers and planning committee was reviewed in accordance with the AAAAI Disclosure Policy. All potential conflicts of interest were mitigated by the planners, faculty and reviewers prior to their participation in the development of this activity.
Planning Committee
Monica Kraft, MD
The Ohio State University Werner Medical Center, Westerville, OH
Relevant relationships: None
Rose Monahan, MD
University of California San Francisco
Relevant relationships: None
Michael Schatz, MD FAAAAI
Kaiser Permanente Medical Center, San Diego, CA
Relevant relationships: None
Christine Panganiban, MD MS
Hoag Medical Group, Foothill Ranch, CA
Relevant relationships: None
Moderator
Christine Panganiban, MD MS
Hoag Medical Group
Relevant relationships: None
Faculty
Ross Tanis, MD
Allergy & Asthma Physicians
Relevant relationships: None
Gerald Teague, MD
University of Virginia
Relevant relationships: None
Brynne Underwood, MD
Cincinnati Children's Hospital Medical Center
Relevant relationships: None
Michelle Huffaker, MD FAAAAI
Immune Tolerance Network, UCSF / Allergy and Asthma Medical Group of the Bay Area
Relevant relationships: None
Content Reviewer
Amanda Louise Cox, MD FAAAAI
Icahn School of Medicine at Mount Sinai
Relevant relationships: None
AAAAI Disclosure Policy
Pursuant to the Code of Ethics for the American Academy of Allergy, Asthma & Immunology (AAAAI) and the Standards for Commercial Support of Continuing Medical Education of the Accreditation Council for Continuing Medical Education, the AAAAI requires disclosure of certain information from faculty members of educational activities designated for CME credit by the AAAAI. Prior to the activity, authors and reviewers are required to disclose all relationships that meet the following parameters:
- Employment: Name of employer and job title.
- Financial interests: All organizations, other than the employer, from which the faculty member or a member of his/her immediate family or household receives annual remuneration in any amount (including grants, honoraria and consulting fees).
- Research interests: All organizations which support research projects for which the faculty member or member of his/her immediate family or household serves as an investigator.
- Legal Consultation Services/Expert Witness Testimony: All topics on which the faculty member provided legal consultation and/or expert witness testimony during the previous calendar year.
- Organizational interests: All organizations, other than the AAAAI, for which the faculty member holds volunteer positions.
- Gifts: All organizations from which the faculty member or a member of his/her immediate family or household have received a gift of any amount in the last year.
- Other interests: All interests of the faculty member or a member of his/her immediate family or household that would be judged by a majority of his/her peers to be more than casual and/or likely to impact his/her ability to exercise independent judgment. This includes any financial interest in or relationship with any manufacturer of a commercial product, and any financial interest or relationship with any organization that provides commercial support to AAAAI-sponsored educational activities.
Accreditation Statement
The American Academy of Allergy, Asthma and Immunology (AAAAI) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Designation Statement
The American Academy of Allergy, Asthma & Immunology designates this other activity (live webinar & video recording) for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Credit Claiming Period
Credit claiming for this activity will expire at 11:59 pm on May 31, 2026. Requests to claim credit on or after June 1, 2026 will be subject to an administrative fee.
Questions
Activity-related questions should be directed to [email protected]
Registration and credit claiming questions should be directed to [email protected]
Available Credit
- 1.00 AttendanceAttendance credit.
- 1.00 CMECME credit.
Price
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Internet Explorer is no longer supported.

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