The World Trade Center collapse significantly impacted rescue workers, and provides a longitudinal look at respiratory disease management over time that can be applied to other occupational and environmental exposures.  Mechanisms by which environmental/occupational exposures impact airway disease will be reviewed for application to future clinical approaches.

LEARNING OBJECTIVES:
Upon completion of this activity, participants should be able to:

• Identify distinct occupational asthma phenotypes and how that information guides potential biological and interventional therapy approaches
• Examine the longitudinal airway disease effects in rescue workers and asthmatics following the World Trade Center collapse, and their implications for treatment
• Identify the mechanisms that determine how differing occupational and environmental exposures impact the airway inflammatory response to guide future therapeutic approaches

Moderator Introduction
David  I. Bernstein, MD FAAAAI
Bernstein Allergy Group, Inc

Phenotyping Occupational Asthma: Is there a Place for Biologics?
Joaquin  D. Sastre, MD PhD FAAAAI
Fundacion Jimenez Diaz

Airway Inflammatory Response Following Differing Occupational/Environmental Exposures: Clinical Implications
Hae-Sim Park, MD PhD FAAAAI
Ajou University School of Medicine

Assessing Long-Term Respiratory Consequences and Management of the World Trade Center Collapse to Inform Current/Future Events
Jacqueline Moline, MD MSc
Northwell Health

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