Aspirin exacerbated respiratory disease (AERD) represents a mix of patents with and without atopy. Locally or systemically produced antibodies may play a role in AERD severity and treatment outcomes. This session will discuss the role of IgE and IgG antibodies in nasal polyps, the role of Th2A cells and serum IgE in AERD, and the comparison of the transcriptomic characteristics of nasal polyps from ethnically diverse patients with and without AERD.
Upon completion of this activity, participants should be able to:
- Define the role of Th2A cells and serum immunoglobulin E on aspirin treatment outcomes in AERD patients
Define AERD nasal polyps by the presence of local antibodies
Compare transcriptomes of nasal polyps from ethnically diverse patients with and without AERD