Early life respiratory infections are major determinants of childhood asthma. This symposium will review the latest data on the contribution of infectious agents to childhood asthma inception, phenotypic-based approaches for the management of asthma among preschool children, and approaches for primary prevention of childhood asthma.

LEARNING OBJECTIVES:
Upon completion of this activity, participants should be able to:

• Describe the role of early life bacterial and viral infections in asthma inception
• Identify phenotype-based therapy for the prevention of asthma exacerbations among preschool children
• Discuss clinical trials aiming for asthma prevention

Moderator Introduction
Stanley  J. Szefler, MD FAAAAI
Children's Hospital Colorado

Microbes and the Inception of Childhood Asthma: Hot Topics
Kirsten  M. Kloepfer, MD MS FAAAAI
Indiana University

Primary Prevention of Asthma: What’s Done and Ongoing Trials
Fernando  D. Martinez, MD
University of Arizona

Phenotype-Based Approach for the Management of Asthma Among Preschool Children
Leonard Bacharier, MD FAAAAI
Washington University

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