Upon completion of this activity, participants should be able to:

• Describe the immunopathology of adverse drug reactions including the Gell & Coombs classification system, pseudoallergic reactions, and the hapten hypothesis
•  Define contraindications to re-exposure to medications implicated in drug allergy including serious cutaneous adverse reactions (SCARs) and end-organ dysfunction (hemolytic anemia, drug induced lupus, etc).
• Describe the role of skin testing, graded dose challenge and desensitization in the evaluation and treatment of patients with drug allergy